Israel’s Cardiacsense watches over your heart; Technion develops artificial skin, allowing burn victims to feel again; Israel’s BrainStorm gets FDA approval for phase 2 trial of Nurown stem-cell treatment for Multiple Sclerosis; and much more!

By Michael Ordman

ISRAEL’S MEDICAL ACHIEVEMENTS

The watch that watches you

I reported previously (Jun 2017) on Israel’s Cardiacsense and its watch that watches over your heart. Its sensors monitor heart activity and blood pressure. For those at risk of stroke or cardiac arrest it can detect arrythmia, arterial fibrillation and alert doctors. Watch COO Liat Shemesh on ILTV.
https://www.youtube.com/watch?v=dORVCXW_jxc  https://club.tgt.co.il/en/project-35/cardiacsense/

Engineering meets medicine for maximum impact

Engineers, researchers and physicians at Israel’s Technion literally work “hand in glove.” They developed artificial skin so burns victims can feel again. A robotic system to perform brain and spine surgery. Ingestible chemotherapy nano-delivery tubes and more.
https://www.timesofisrael.com/spotlight/engineering-meets-medicine-for-maximum-impact/

Stem cell treatment for MS

Israel’s BrainStorm has received FDA approval to use its Nurown stem cells in a Phase 2 trial for the treatment of Multiple Sclerosis (MS). MS affects approximately 1 million individuals in the U.S. and 2.5 million individuals worldwide.  Nurown is already in a Phase 3 trial for ALS (see here).
https://globenewswire.com/news-release/2018/12/17/1667840/0/en/FDA-Accepts-BrainStorm-s-NurOwn-IND-Application-for-Progressive-Multiple-Sclerosis.html

Targeting bone marrow to destroy tumors

Israeli researchers at Tel Aviv University have discovered that breast cancer tumors boost their growth by recruiting stromal cells that originate in bone marrow. Targeting these cells with new therapies could be an effective way of treating the deadly disease.
http://www.jewishpress.com/news/health-and-medicine/breast-cancer-grows-by-recruiting-cells-from-bone-marrow/2018/12/11/    http://jem.rupress.org/content/215/12/3075

Revealing the secrets of multiple myeloma

Scientists from Israel’s Weizmann Institute together with other Israeli blood cancer experts, have captured the specific gene program active in each individual cell. They can now identify pre-cancer cells, for early diagnosis and treatment of the deadly multiple myeloma disease.
https://wis-wander.weizmann.ac.il/life-sciences/profiling-killer-warm-blood
https://www.nature.com/articles/s41591-018-0269-2

New pathway may alleviate anxiety

Anxiety disorders can affect billions of people. Scientists at Israel’s Weiizmann Institute have discovered a new neural mechanism underlying anxiety. It involves protein importin alpha-5, gene MeCP2 and signal molecule S1P. Targeting this biochemical pathway may lead to new therapies.
https://wis-wander.weizmann.ac.il/life-sciences/importins-anxiety
http://jem.rupress.org/content/215/12/3075

Groundbreaking CT-Scanning

The Radiology department at Israel’s Hadassah Medical Center in Jerusalem has been conducting joint research with Philips Medical Systems. It has resulted in a laboratory to study dual energy CT techniques using an experimental IQon Spectral CT scanner that is the first of its kind in the world.
http://www.spectralctlearningcenter.philips.com/
http://www.israel-radiology.org.il/images/ISRA2017Abstracts.pdf

New Israeli faculty for Medicinal Chemistry

Thanks to a major donation, Israel’s Weizmann Institute is establishing the Dr. Barry Sherman Institute for Medicinal Chemistry. Scientists will research compounds that can become therapies for autoimmune diseases, cancer, neurodegenerative diseases, and infectious diseases.
https://wis-wander.weizmann.ac.il/life-sciences/weizmann-institute-science-establishes-dr-barry-sherman-institute-medicinal-chemistry  https://en.wikipedia.org/wiki/Barry_Sherman

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